In the first part the meaning of terms cognition and cognitive dysfunction is clarified. Cognitive dysfunction is found
in many neuropsychiatric disorders. Majority of studies were done in patients with schizophrenia and dementia. For
studying cognitive dysfunction, the most appropriate appear the initial phases of the disease. The next part of the study
summarizes the treatment possibilities of cognitive dysfunction in schizophrenia. Atypical antipsychotics represent
the basal treatment. The improvement of cognitive deficit by atypical antipsychotics is significant, but its importance
in real life is small. The new add-on treatment has the potential for further improvement of cognitive
dysfunction. This approach includes augmenting effects of neurotransmitters related to cognition (glutamate, noradrenalin,
serotonin, acetylcholine). The improvement of cognitive dysfunction can improve the long-term outcome and
functional prognosis in patients suffering from schizophrenic disorder.
cognitive dysfunction, schizophrenia, dementia, atypical antipsychotics add-on treatment, augmentation.