Background. In midpregnancy, more than 3000 women in Brno filled in the questionnaires for the ELSPAC study.
They informed of their health, activities, stress and psychological state during this pregnancy.
Methods and Results. Out of medical documentation, the results from routine prenatal examinations were
extracted and records concerning all disorders occurred during the gravidity. After delivery, information comming
from both sources were linked to the birth weight (BW) and gestational age (GA) data of newborns and analysis of
variance was performed. In statistically significant relations the differences were stated in BW (grams) and in GA
(weeks) between the group means and sample means for boys, girls and all newborns together. BW, GA or both
values were significantly lower after taking some medicaments, alcohol drinking, in offsprings of mothers who felt
feeble around the quickening, who worked part time, who were in leading position in their employments, who
experienced serious disease, who tempted a suicide, who worried that the foetus might be handicapped in any way
and who did not take their future motherhood for a priority. Heavier were newborns of women who married during
pregnancy and longer GA had children of those who took folic acid. The relation of neurotic symptoms to the outcome
of pregnancy was not found and stressogenic events showed only a limited effect on it. A strong deficit in BW and
GA followed after premature abruption of placenta, after eclampsia, placenta praevia, cervical cerclage, partus
premature imminens, bleeding in the 2nd trimester, hypertension and hospitalization, namely when repeated. BW
only was lower with IUGR, oligohydramnion, and higher BW followed after oedemas. GA only was affected in
those whose mothers omitted the sonographic examination and who were obliged to have a special diet.
Conclusions. When newborns BWs were divided into 8 classes by 500 g and some maternal characters follow ed
across the scale, significant trends were found in maternal heights, in all their weight indicators including maternal
BW as well as in the weight gain in pregnancy, in the highest means found during pregnancy of systolic and diastolic
blood pressures and in the lowest haemoglobin levels.
birth weight, gestational age, risk factors, disorders of pregnancy, body size of mothers, activities in
pregnancy, stress, neurotic symptoms, epidemiologic study.