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  Česky / Czech version Čas. Lék. čes., 2006, 145, pp. 599–605.
 
Pancreatic Hormones and Hormonal Regulation of Insulin Secretion 
Škrha J. 

III. interní klinika 1. LF UK a VFN, Praha
 

Fulltext


Summary:

       Endocrine pancreas producing insulin, glucagon, somatostatin and pancreatic polypeptide is under the influence of different types of regulation; among them the regulatory role of enteropancreatic axis plays an important role. Incretin effect of glucose-dependent insulinotropic peptide (GIP) and glucagon-like peptide 1 (GLP-1) is significantly involved in the insulin secretion which is modulated by many other hormones. Diabetes mellitus, similarly to disturbances of other hormones, can cause impaired regulation of insulin and other pancreatic hormones.

        Key words: pancreatic hormones, insulin secretion, incretin hormones.
       

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