Syndromology belongs to diagnostic methods based on the analysis of phenotypic (clinical or anatomical – dysmorphics)features,which occur very often together and have a common etiology (e.g.teratogenic embryopathy, numerical and structural chromosomal aberrations or gene mutations).In the phenotype analysis important appear so-called signal features,which enable to narrow the range of possible disorders for the differential diagnosis of the assumptive diseases.

        Key words: syndromology,dysmorphology,signal features,etiology of syndromes.