The aim of the study was to analyse the group of patients with cutaneous malignant melanoma in whom the new primary tumour was diagnosed successively. The source of patient group was database of oncological reports of The National Oncological Register of the Czech Republic in the years 1991 -2000. The analysis focussed on the sex, age in the time of melanoma diagnosis, melanoma localization and histopathological classification and the interval between melanoma and second tumour diagnosis. Further, the ratio of the second malignity type and occurrence of multiple malignancies was analysed. The most frequently diagnosed duplicities were the skin tumours (52%), from non-skin malignancies the colorectal, breast, prostate, renal and lung carcinoma were diagnosed in 8%, 6%, 4% and 3.5% of cases respectively.

        Key words: malignant melanoma - multiple malignancy - The National Oncology Register