Background. Chest pains are related to coronary disease, and to several other disorders, among which the most commons are the oesophageal diseases. The aim of the work was the identification of the reflux oesophagitis in patients with chest pain and normal selective coronary angiogram. Methods and Results. In the examined group 65 patients (42 females, 23 males) of the average age 55,2 years were included. All of them underwent endoscopic investigation with biopsy from the terminal part of the oesophagus. Endoscopy picture was evaluated according Savary-Miller classification. Biopsy samples were histologically examined and evaluated according our proper classification of the reflux oesophagitis (1st degree: mild, 2nd degree: medium, 3rd degree: heavy, 4th degree: ulcerous). Endoscopical finding was normal in 59 patients (90.8 %), reflux oesophagitis of the 1st degree in 2 patients (3.1 %) 2nd degree in one patient (1.5 %), 3rd degree in 2 patients (3.1 %), 4th degree in one patient (1.5 %). Histological changes which can be included into the picture of so called microscopic oesophagitis were found in 49 patients (75.4 %). The rest of patients had the histology picture normal. Conclusion. In 75.4 % of patients with chest pain and negative selective coronary angiogram histological examination revealed structural changes corresponding with oesophagitis, mostly of the mild type.

        Key words: oesophagitis, retrosternal pain, angiography, histology.