Peripheral Arterial Occlusive Disease versus Depression Symptoms and
Quality of Life
1,2Slováček L., 3Slováčková B., 4Chovanec V.
1Katedra válečného vnitřního lékařství, Fakulta vojenského zdravotnictví Univerzity obrany, Hradec Králové 2Oddělení klinické hematologie, II. interní klinika LF UK a FN, Hradec Králové 3Psychiatrická klinika LF UK a FN, Hradec Králové 4Radiodiagnostická klinika LF UK a FN, Hradec Králové
Background. The study has three main aims: 1. it evaluates occurrence of depression symptoms in patients with
peripheral arterial occlusive disease (PAOD), 2. it evaluates global quality of life (QoL) in patients with PAOD and
3. it evaluates effect of age and stage of PAD on seriousness of depression symptoms and on the QoL in patients with
PAOD. Patients and Method: the study is local, prospective and cross-sectional. It was carried out at the 2nd Internal
Clinic of University Hospital in Hradec Králové. Data were obtained during the year 2006.
Methods and Results. The total number of respondents with PAOD was 42 (28 male, 14 female). The average age
of all respondents with PAOD was 65.4 years and age range was 45-79 years. The evaluation of occurrence of depression
symptoms in patients with PAOD was performed by means of self-assessment Zung-SDS and evaluation of QoL
in patients with PAOD was performed by means of Czech version of international generic European Quality of Life
Questionnaire – EQ-5D Version. Statistical significance was determined by means of analysis of variance. Main
The mean SDS index certifies the presence of signs of minimum or light depression in patients with PAOD. The QoL
in patients with PAOD is on the low level. The above-mentioned aspects proved statistically significant dependence
of QoL in patients with PAOD on depression (p<0.001), on age (p<0.01) and on stage of PAOD (p<0,01). We proved
statistically significant dependence of depression in patients with PAOD on age (p<0.01) and on stage of PAOD
Conclusions. The results show the existence of the association between PAOD and depression symptoms with its
negative effect on QoL in patients.
peripheral arterial occlusive disease, depression symptoms, quality of life.