|CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ|
|Journals - Article|
|Česky / Czech version||Čes. slov. Farm., 2004; 53, 192–196|
Analysis of Tablets Containing the Antihistamine Loratadine: A Contribution to the
Identification of Impurities
ISSA N., MLYNÁROVÁ M.
Štátny ústav pre kontrolu liečiv, Bratislava
Thin-layer chromatography on silica gel (Merck) was employed to examine potential impurities
present in loratadine-containing tablets. A method usable for testing of impurities was elaborated,
which suitably supplements the determination of loratadine content using the spectrophotometric
method in the UV region. The method was validated for selected pharmaceuticals.
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