Cerebral ischemia is a frequent and dangerous consequence of some cerebrovascular diseases. Ischaemia may be
used also electively in the course of neurosurgery. Therefore new possible ways are sought how to reduce the danger
of ischaemia or to prevent it.
In the submitted paper some methods of neuroprotection are described and their potential or actual applicability
in clinical neurosurgery are discussed. In addition to influencing the brain cell and pretentious methods in the sphere
of molecular biology and genetics the induction of systemic hypertension supplemented alternatively by other
methods such as hypothermia, the use of mannitol, haemodilution and hypervolaemia seem natural. A higher blood
pressure helps to make leptomeningeal and cortical anastomoses patent and strengthens the collateral circulation
from marginal zones of ischaemia, penumbra to the ischaemic centre and to prevent thus cerebral infarction.
cerebral ischaemia, neuroprotection.