This review presents a survey of preparations and biological activities of substituted benzoxazoles.
The structural similarity of benzoxazole derivatives with nucleic bases, such as adenine andguanine,
probably allows their easy interaction with biopolymers in the living systems. Consequent- ly, these
compounds posses a wide range of biological activities. Their preparation includes cyclocondensation
reactions and contractions of ortho-fused heterocycles or their photochemical rearrangement.
They are being studied predominantly for their antibacterial, antifungal, antiviral, and
antitumor activities, and also as insecticides, herbicides, anthelmintics, histamine antagonists, and
benzoxazole – 2-aminophenol – biological activity – antimicrobial activity