Fluorescence Cystoscopy with 5-Aminolevulinic Acid
Jirsa M., 1Babjuk M., 1Petřík R., 1Dvořáček J. , 2Urban M. , 3Köhler O.
I. interní klinika 1. LF UK a VFN, Praha 1Urologická klinika 1. LF UK a VFN, Praha 2Urologická klinika 3. LF UK a FNKV, Praha 3Urologické oddělení ÚVN, Praha
Background. Fluorescence diagnosis has an increasing importance in differentmedical fields. In the presented paper,
comparison of cystoscopy in white light with fluorescence cystoscopy after intravesical administration of 1 g of
5-aminolevulinic acid is presented.
Methods and Results. From the group of 63 persons examined, no difference between findings in white and blue
light was found in 39 cases. In 21 patients more pathological spotswere found in blue light (10 cases) or, in agreement
with histology, pathology was detected in the blue light only (11 cases).
Conclusions. The intravesical administration of 5-aminolevulinic acid had no side effects. Our study has definitely
proved the advantages of fluorescence cystoscopy.
fluorescence cystoscopy, photodynamic diagnostic, 5-aminolevulinic acid.