The fractal character of exponential particle size distribution makes it possible to use fractal
dimension for the evaluation of the results of granulometric analysis. The conditions of sedimentation
analysis of talc in aqueous solution were optimized by adding nonionogenic tenside and
deflocculation electrolyte. Dispersion analysis demonstrated the suitability of minimally 0,2 g/l of
polysorbate 80 for talc soaking. In the evaluation of pharmaceutical granulometry, it is advisable to
supplement the usually reported specific surface area with fractal dimension, which primarily
contributes to a more general interpretation of variability of particle size.
particle size analysis – fractal dimension – particle size distribution – talc