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  Česky / Czech version Čes. a slov. Farm. 48, 1999, No. 4, p. 147–155
 
Advances in the Development of New Antituberculotics of the Group of Five-Membered Heterocyclic Compounds Containing One Species of the Heteroatom 
WAISSER K., DRHOVÁ L. 

 


Summary:

       Tuberculosis and other mycobacterial diseases are considered at present to be one of the prominent problems of health services. Since 1985, and in particular in the 1990s, a search for new structures of antimycobacterial drugs is one of the first and foremost fields of chemotherapeutic research. The present review paper surveys the studies carried out in the field of five-membered heterocyclic compounds containing one species of the heteroatom (furan, thiophene, pyrrol, diazoles, triazoles, tetrazoles, indol, carbazol, and other more complex cyclic compounds of nitrogen and sulfur) since 1984, making use of the journal Chemical Abstracts and original papers.

        Key words: tuberulostatics – five-membered heterocycles – mycobacteria
       

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