Pemhigus vulgaris is an autoimmune bullous disease of the integument. When not treated, it has a high mortality, the
treatment with corticosteroids and immunosuppressives has serious side effects. Our casuistry gives a case of patients
with histologically verified diagnosis of pemphigus vulgaris. In this case the stabilization of the disease was difficult
and side effects of the combined immunosuppressive therapy developed very early.
pemhigus vulgaris, immunosuppressive therapy, undesired side effects.