Proteomics is a new methodological and conceptual approach to the study of live systems, which aims to map the
whole proteom - the protein complement of genome. It aspires to describe quantitatively and qualitatively all proteins
present at the given moment in the cell, tissue or the organism. The principal tools of proteomics are separation
techniques based on electrophoresis and chromatography, which are used to fractionate complex protein mixtures and
namely the mass spectrometry used for the identification of individual proteins. Proteomics represents very young and
rapid developing specialization, which has already proved its valuable potential for the study of various physiological
and pathlogical molecular mechanisms and for the direct use in the diagnostics of serious diseases.¨
proteomics, proteome, two-dimensional electrophoresis, chromatography, mass spectrometry.