The statistic analysis of a large group of patients with neurological analysis enabled elucidation of biological role ofCSFproteins evaluated; in with comparison with clinical data of these patients, specific clinical syndromes of CSF proteinogram were defined. Previously, CSF proteinogram was introduced to routine clinical practice for diagnostics of neuroinfective and autoimmune diseases of CNS and PNS; after that, the concrete definition of clinical syndromes of CSF proteinogram enables routine diagnosis of inflammatory and autoimmune diseases of nervous system.

        Klíčová slova: CSF, CSF proteins, CNS.