The study is a review paper about the development of antituberculous substances in the group of
quinazoline derivatives. Most antituberculous compounds under study contain the pertinent phar-
macophores in the functional groups and their antituberculous activity cannot be considered to be
specific for quinazolines. Nevertheless, several groups of antituberculously effective quinazoline
derivatives were found which do not contain the known pharmacophores of antituberculous activity.
The substances are, on the rule, of medium activity, but the activity of some of them, evaluated in
vitro, approaches that of commonly used antituberculous agents. They can thus initiate new r esearch
in this direction. The present paper is already the 12 th communication in a series of review papers
about substances with antituberculous activity.
tuberculostatics – mycobacteria – antituberculous agents – quinoxaline