Background. An inverse relationship between moderate alcohol use and coronary heart disease was found in various countries. Aims of the study were to řmd out whether drinking of moravian white wine will have the same effect on lipoproteins and fibrinogen as described in foreign wines. Blood pressure, body mass, blond glucose and a hepatic enzyme were also measured before and after drinking. Methods and Results. Drinking of the Moravian white wine (vintage 1999; alcohol 11.48 vol %) was studied in 50 men aged 44.4 (SD 9.25) years. Drinking of 350 ml (40.2 g of alcohol) every evening for four weeks without any change of dietary factors followed in 45 men by statistically signi%cant increase in HDL cholesterol from 1.17 to 1.25 mmol/1 (p<0.001) and free HDL cholesterol from 0.17 to 0.20 mmol/1 (p<0.0001) and highly significant (p<0.00001) decrease in plasma %brinogen level from 3.77 to 3.35 g/1. Nor triglycerides, or blond glucose and BMI were changed after increasing Bource of carbohydrates in wine. Mean systolic blond pressure of 123.4 mmHg did not change and diastolic blond pressure decreased insigni%cantly from 78.0 to 76.7 mmHg. Minimal decrease of ALT from 0.60 to 0.59 pkat/1 disproved any hepatic disturbance. Conclusions. Everynight moderate drinking of Moravian white wine has similar bene%cial effect as consumption of foreign alcohol drinks.

        Key words: lipoproteins, HDL cholesterol, fibrinogen, blond pressure, glycemia, ALT, BMI.