The authors present basic technical prerequisities for safe administration of nitric oxide (NO). Characteristics of its administration, principles of NO a NO2 analysis and development trends of those equipment are outlined. The present philosophy on nitric oxide application is demonstrated on the development line of Austrian company Messer Austria; its main advantage is compatibility with all generally used mechanical ventilators.

        Key words: nitric oxide – nitric superoxide – continuous flow system (CFS) – chemiluminiscent analyzer – electrochemical analyzer – flowbox – ventilator