The paper deals primarily with the study of biological properties of a model of implant covered with a thin layer of hydroxyapatite with an intermediate layer of zirconium. Cytotoxicity was evaluated by direct cultivation with mouse and human fibroblasts. A physical test using X-ray diffraction confirmed that the film is composed of crystalline hydroxyapatite. The evaluation of the cytotoxicity test and a comparison with controlled samples cultured in parallel in vitro made it possible to conclude that the material is not cytotoxic audit is suitable for further experiments in more detail.

        Key words: implant – hydroxyapatite – zirconium – X-ray diffraction – direct cytotoxicity test