Since November 1998, all patients with head-brain injury admitted to the Department of Anaesthesia and Imensive Care, Trauma Hospital Brno are enrolled to prospective study and treated according to the protocol issued by i1S-Aitken Brain Trauma Foundaxion. Ourpaper presems the clinical situation of severe head-brain injury combined with polytrauma. Pitfalls of the treatmem, monitoring and hnal outcome are presented in the paper.

        Key words: severe brain injury - other system injury - multimodal monitoring - intracranial hypertension - hemodynamic instability - outcome