Human hepatocytes (HH) are an optimal in vitro model for the study of xenobiotics metabolism and
toxicity. However, there is still a problem of HH availability. A promising possibility for the storage
of HH for later utilization is cryopreservation. Procedures and conditions used for cryopreservation
of human hepatocytes and hepatocytes of other species are presented in the present paper. Compared
are some biochemical parameters characterizing viability and functionality of fresh and thawed HH.
human hepatocyte – cryopreservation – viability – metabolism