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  Česky / Czech version Prakt. Lék., 2004, 84, No. 10, p. 572-576. Čes.-slov. Patol., 2003, 39, No. 3, p. 120 - 125.
 
New Aspects in the Field of MALT Lymphomas of the Stomach 
SOUKUP J., KRSKOVÁ L., CAMPR V. 

Ústav patologie a molekulární medicíny 2. LF UK a FN Motol, Praha
 


Summary:

       The knowledge about MALT lymphomas has dramatically changed in the last few years. The genesis of MALT lymphomas has become clearer, and new tools in modern diagnostics are available. This article, as a concise review, summarises the latest data and the clinical and morphological characteristics with the aspect of routine diagnostics. The characteristic translocation t(11;18) and its chimeric transcript API2-MALT1 with antiapoptotic function is emphasised.

        Key words: MALT lymphoma – BCL10 – API2 – MALT1 – IgH.
       

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