The Use of Mechanical Circulatory Support – Early Experiences in the Czech Republic
Kettner J., 1Pirk J., 1Netuka I., 2Březina A., 2Říha H., 1Malý J., 1Mašín J.
Klinika kardiologie IKEM, Praha 1Klinika kardiovaskulární chirurgie IKEM, Praha 2Klinika anesteziologie a resuscitace IKEM, Praha
Background. Implantation of mechanical assist device is widely accepted modality of treatment of patients with refractory
heart failure. In the present study we evaluated our first one-year experiences with this method for bridging
patients to cardiac transplantation.
Methods and Results. Between April 2003 and May 2004, the Thoratec® VAD (Thoratec, Pleasanton, CA, USA)
was implanted in 6 patients ( males; age 28–61 years) as a bridge-to-transplant procedure after having received maximum
inotropic support and who were at imminent risk of death. In all patients was performed VAD as biventricular
During a week after placement was observed recovery of organs function in all patients. Five patients survived to
heart transplantation. One patient died 21 days after BiVAD placement due to massive bleeding to the respiratory
tract. In post-transplantation period 1 patient died second day from acute graft failure and other patient died 34 days
after from intracranial bleeding. Three patients has been discharged from the hospital and they are surviving more
than 1 year.
Conclusions. Analysis of our first experiences with the Thoratec BiVAD implantation as bridging to heart transplantation
suggests that it is well suited method with respect to long- term prognosis of this group of patients.
heart failure, mechanical assist devices, heart transplantation.