Heart Failure in Hypertensive Patients with left Ventricular Hypertrophy
Ghanem Wisam M. A., Mikeš P., Bulas J., Kozlíková K., Sleiman O., Murín J., Reptová A
I. interná klinika Lekárskej fakulty UK a Fakultná nemocnica, Bratislava, prednosta prof. MUDr. Ivan Ďuriš, DrSc. |
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Summary:
Left ventricular hypertrophy (LVH) is supposed to be a useful marker of cardiovascular complications during the course of hypertension. Authors compared the presence of heart failure, left
ventricular diastolic dysfunction and chronic atrial fibrilation in hypertensive patients with and
without left ventricular hypertrophy defined by echocardiography.
Hospital records of 192 hypertensives treated in our medical department during years 1996 - 1999
were analysed. Left ventricular hypertrophy was defined by echocardiography (Penn convention)
as left ventricular mass index > 134 g/m
2
in men and > 110 g/m
2
in women. Presence of LVH was
found in 128 patients (mean age 65.9 years), absence of LVH in 64 patients (mean age 64.8 years).
Both groups of hypertensives were matched by demographic parameteres, by the presence of
hyperlipidemia, by smoking habits. Hypertensive patients with left ventricular hypertrophy were
more often treated by ACE inhibitors.
There were statistically significant more patients with heart failure, left ventricular diastolic
dysfunction and chronic atrial fibrilation in LVH-positive patients than in LVH-negative once.
There was also statistically significant lower ejection fraction (50.3 ± 11.4 % vs 56.5 ± 7.4 %) in
LVH-positive patients than in LVH-negative once.
Left ventricular hypertrophy in patients with hypertension brings usually a complicated course
of the disease with a high contribution to the development of chronic heart failure.
Key words:
Left ventricular hypertrophy - Arterial hypertension - Heart failure - Left ventricular
diastolic dysfunction - Atrial fibrillation - Ejection fraction
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