So-called Idiopathic Epilepsy and Genetic Factors in Etiological Diagnostics: Real Cause
or Accidental Coincidence?
Varsik P., Buranová D., + Brežný I., Goldenberg Z., Kollár B., Kondáš M., Traubner P.
I. neurologická klinika FN a LF UK Bratislava, Slovenská republika |
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Summary:
In the literature the term —idiopathic epilepsyii is frequently used in cases, where the etiological factor
was not determined. Up to 70% of cases are diagnosed as —idiopathic epilepsyii and 80% of epileptic
seizures originate before the age of 25 years. Development of structural lesions in the brain and
influence of genetics are very important factors in the etiology of epilepsy. In this paper cases of four
patients are discussed. Conclusions: even determination of the genetic factor does not exclude that
epilepsy is a syndrome with many etiological factors. The relative importance of perinatal factors,
nutrition, trauma and other environmental influences must be considered. In our opinion, the term
"idiopathic epilepsy" is incorrect, inaccurate and we propose a more appropriate term "epilepsy"
("epileptic syndrome") of "unclear" or "uncertain genesis".
Key words:
idiopathic (genuine, cryptogenic) epilepsy, etiology of epilepsy, congenital causes of
epilepsy
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