The authors assessed the diagnostic accuracy of some laboratory tests in Wilson™s disease. They used ROC analysis and compated patients with Wilson™s disease with patients suffering from various hepatopathies but not from Wilson™s disease. The authors suggest to reduce the number of laboratory tests and emphasize the high diagnostic effectiveness of copper estimation in hepatic tissue obtained by biopsy. The presented paper should serve as a model example for the use of ROC analysis in other laboratories.

        Key words: Wilson™s disease, laboratory tests, ROC analysis.