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  Česky / Czech version Čes. a Slov. Neurol. Neurochir., 61/94, 1998, No. 6, p. 312–320.
 
Relationship between Mortality from Spontaneous Intracranial Haemorrhages and the Size, Site, Behaviour of the Haemorrhage and the Patients’ Age 
Herzig R., Buřval S., Vlachová I., Urbánek K., Křupka B. 

Neurologická klinika LF a FN, Olomouc
1 Radiologická klinika LF a FN, Olomouc
 


Summary:

       Objective: The objective of this retrospective study was to evaluate the relationship between the mortality from spontaneous intracranial haemorrhages and the size, site, behaviour of the haemorrha- ge and the patients’ age. Clinical group and methods: The authors evaluated a group of 202 patients with spontaneous intracranial haemorrhages. Of 137 intracerebral haemorrhages 46% were in the basal ganglia, 31% were lobar, 11% in the thalamus, 7% in the cerebellum and 5% in the brain stem. In all patients the site of the haemorrhage was evaluated by CT as well as its size (according to the longest axis) and the midline-shift. The authors investigated the relationship between 30-day mortality, the above mentioned factors and the patients’ age. The statistical significance was evaluated by means of the c 2 test. Results: The mortality from intracerebral haemorrhages increased significantly with the patients’ age: 10–49 years: 0%, 50–59 years: 10 %, 60–69 years: 29%, 70–79 years: 43%, 80–99 years: 54% (p = 0.00002). There was also a significant age-conditioned increase of mortality from subarachnoidal and intraventricular haemorrhages – 10–59 years: 0%, 60–79 years: 31%, 80–99 years: 50% (p = 0.0009). The mortality of supratentorial intracerebral haemorrhages without the intraventricular component (and with the intraventricular component resp.) increased significantly in relation to the size of the haemorrhage – 1–19 mm: 0% (17%), 30–39 mm: 19% (40%), 40–49 mm: 15% (40%), 50–69 mm: 36% (36%), 70–99 mm: 44% (89%) (p = 0.04 and p = 0.05 resp.). The authors also provided evidence of a close correlation between the increase in mortality from spontaneous intracranial haemorrhages and the midlineshift – 0 mm: 12%, 1 mm: 30%, 2 mm: 31%, 3 mm: 46%, 4 – 7 mm: 50%, 8 – 11 mm: 56%, 12 – 30 mm: 67% (p = 0.00002). Conclusion: The mortality from spontaneous intracranial haemorrhages increases signi- ficantly in relation to the patients’ age and the midline-shift associated with the haemorrhage. The mortality from spontaneous supratentorial intracerebral haemorrhages increases significantly in relation to the size of the haemorrhage and intraventricular penetration of blood. The evaluation of the above factors can be used for prediction of the condition development of patients with those haemorrhages. Key words: spontaneous cerebral haemorrhage, prognosis, mortality

        Key words: spontaneous cerebral haemorrhage, prognosis, mortality
       

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