Our experíence with pulmonary symp-toms in patients with inflammatory bowel diseases.
PAZOURKOVÁ M.1'4, TOMANDL J.2, BRHEL P.1, PROKOPOVÁ L.\ SKŘIČKOVÁ J.4
1Klinika pracovního lékařství Lékařské fakulty MU a FN u sv. Anny, Brno, Přednosta: prof. MUDr. Petr Brhel, CSc. 2Biochemický ústav Lékařské fakulty MU a FN Brno, Přednosta: prof. MUDr. Vladimír Palyza, CSc. ^Interní hepatogastroenterologická klinika Lékařské fakulty MU a FN Brno, pracoviště Bohunice, Přednosta: prof. MUDr. Petr Dítě, DrSc. 4 Klinika nemocí plicních a tuberkulózy Lékařské fakulty MU a FN Brno, Přednosta: doc. MUDr. Jana Skřicková, CSc. |
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Summary:
Extraintestinal manifestations of inflammatory bowel diseases (IBD) represent a continuum stretching from separate symptoms to independent nosological entities oveiiapping from gastroenterology to a variety of other internal medicíně subspecialties. In this study, respiratory diseases involved in IBD were analyzed. A particular IBD čase of 12-year duration complicated with chronic obstructive pulmonary disease (COPD) illustrates some etiopathogenetic and diagnostic problems as well as the pitfalls of differentiation between the categories of systemic or associated diseases.
The contribution of multifactor risk factors such as smoking is evaluated. These factors make it even more difficult to assess whether pulmonary disease is a complication of IBD or an independent, concomitant disease. The available evidence is further limited by eventual smoking history. The diagnosis and treatment should be doně in close coordination with relevant specialists.
Early detection of secondary respiratory disease in IBD can be secured by regular follow-up of patients, lung function tests, and early chest HRCT examination in čase of doubt. In risk groups, the likelihood of pulmonary fibrosis should also be kept in mind.
Key words:
idiopathic intestinal inflammations, inflammatory bowel disease, Crohn's disease,ulcerative colitis, extraintestinal manifestation, pulmonary symptoms, bronchitis, bronchiectasis
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