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CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ |
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Česky / Czech version | Vnitř. Lék., 46, 2000, No. 12, p. 839 - 842 |
Helicobacter
Pylori and Non-specific Inflammations of the Gut Münzová H. 1 , Dítě P. 1 , Ševčíková I. 2 , Dolina J. 1 , Novotný I. 1 , Kunovská M. 1 1 Interní gastroenterologická klinika FN Brno, pracoviště Bohunice, přednosta prof. MUDr. P. Dítě, DrSc. 2 Transfuzní oddělení FN, Brno, přednosta prim. MUDr. E. Slavíčková |
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Summary: In 50 subjects with non-specific inflammations of the gut the total prevalence of Helicobacter
pylori positive antibodies was 28%, while in the control group of blood donors it was 54 % Patients
with ulcerative colitis had lower antibodies - 18%, in Crohn´s disease the serum positivity was
33 %. The lowest value of antibodies was found in patients taking Sulfasalazine - 11 %. The serum
positivity was substantially higher in inactive ulcerative colitis and Crohn´s disease - 35 % than in
patients with signs of high activity - 13%. In 28 patients with non-specific inflammations of the gut
endoscopy was performed, in 60 % with a pathological outcome. Histologically confirmed gastritis
was in the majority Helicobacter pylori negative. it may be stated that in patients with non-speci-
fic inflammations of the gut there is a lower incidence of Helicobacter pylori than in the general
population, in particular those subjects who were or are treated with Sulfasalazine. The explana-
tion of this fact is however only speculative.
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