Psoriatric Arthritis
Štolfa J.,Kodeda M.,Gollerová V.,Štorková L.,Galatíková D.,Kopsa P.,Vítek P.,Vlasáková V.,Hanzlíček P.2 ,Kyloušková M.2
Revmatologický ústav Praha,Revmatologická ordinace Pardubice,Revmatologická ordinace Praha, Revmatologická ordinace Příbram,Revmatologická ordinace Bruntál,Revmatologické odd.FTN Praha, Revmatologická ordinace Zlín,Interní oddělení nemocnice Čes.Budějovice,2 EuroMISE Centrum UK a AV ČR |
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Summary:
In the register of rheumatic diseases in November 2001 a total of 207 patients were on records with
the diagnosis of psoriatic arthritis (PsA)according to Wright and Moll ’s definition of 1973.In the
group women predominate (F/M =1.38).The mean age of manifestations of psoriasis (ps.)is 30.4 ±
15.3 (3.0 –70.0,median 30 years).Psoriasis was most frequently manifested in the second decade (in
23.5 %)most frequently the „vulgar “typo of psoriases was involved (91 %).The mean age of
manifestations of psoriatic arthritis (PsA)is 40.7 ±13.5 years (9.0 –75.0,median 42 years),most
frequently PsA was manifested in the 5th decade (in 29.8 %).The mean duration of the disease on
entry into the register is 10.2 ±8.4 (0.0 –40.0,median 8 years),most frequently 0 –5 years (in 36.0 %).
The activity of the disease on a 5 point verbal scale (none,mild,medium,high)very high was
evaluated by the physician most frequently as mild (in 50.2 %),the patients evaluated the activity
of the disease most frequently as medium (43.0 %patients),90 %patients in the register have at least
one clinically damaged joint,the mean number of damaged joints per patient is 6.9 ±7.7 (0 –45,median
4).The mean rate of progression of articular damage is 1.1 ±1.4 (0 –8,median 0.6)damaged joints per
year.The presence of clinically damaged joints,their number or the rate or progression do not
correlate with the erythrocyte sedimentation rate (ESR)nor with the level of C-reactive protein
CRP.At least one erosion is present in 65.2 %patients.The presence of erosions does not correlate
with ESR it correlates however positively with the CRP level.The presence of clinical articular
damage correlates positively with the presence of radiological articular damage (with the presence
of erosions).Sacroiliitis is present on X-ray in 24.6 %patients,syndesmophytes and parasyndesmop-
hytes are present in 20.7 %patients.Type I PsA (with manifestation of psoriasis before the age of 40
years is found in 72.4 %,type II (with manifestation of psoriasis after the age of 40 years)in 27.6 %
patients.In PsA type I clinical articular damage is significantly more frequent (p =0.04),the extent
of articular damage (i.e.the number of clinically damaged joints)however does not differ signifi-
cantly between the two types.The number of patients with erosions does not differ significantly in
the two types of PsA.Ophthalmological manifestations (conjunctivitis or iridocyclitis)were present
in 10.6 %patients,cardiac (aortitis)in 1.5 %and pulmonary also in 1.5 %patients.
Key words:
psoriatic arthritis,psoriasis,clinical articular damage,radiological articular dama-
ge,sacroiliitis
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