Neurologic manifestations of
Takayasu arteritis
Krobot M.1, Štolfa J.2, Krupa P.3, Bečvář R.2, Havelka J.4
1Neurologické oddělení SN, Opava, 2Revmatologický ústav, Praha, 3Klinika zobrazovacích metod FN USA, Brno, 4Radiologický ústav FNsP, Ostrava |
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Summary:
Takayasu arteritis is a rare inflammatory disease affecting large arteries including arteries supplying
the brain. Typical manifestations are stenotic-occlusive vascular lesions leading to ischemization of the
target organ. For determination of the diagnosis, results of vascular imaging examinations are decisive,
with the characteristic pattern of arterial affection allowing differentiation from the far more frequent
atherosclerosis. Pharmacotherapy is effective only in the acute phase; critical chronic lesions require
invasive solutions. The authors present a case report of a 19-year old man with a more than a year-long
history of generalized inflammatory disease in whom the arteries branching off the aortic arch were
affected and who was diagnosed on the basis of sonographic examination of neck arteries. Current
diagnostic and treatment possibilities for this disease are discussed.
Key words:
Takayasu arteritis, large artery vasculitis, atherosclerosis, noninvasive vascular imaging
methods, cerebrovascular accident
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