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CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ |
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| Česky / Czech version | Vnitř. Lék., 50, 2004, No. 1, p. 45 - 53 |
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The Importance of Immunophenotyping
in Diagnosis of B-lymhoproliferative Disorders Prausová D.1, Krejsek J.1, Žák P.2, Voglová J.2, Belada D.2 1Ústav klinické imunologie a alergologie Lékařské fakulty UK a FN, Hradec Králové, přednosta MUDr. Otakar Kopecký, CSc. 2Oddělení klinické hematologie FN, Hradec Králové, přednosta prof. MUDr. Jaroslav Malý, CSc. |
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Summary: The immunophenotyping of the lymphoproliferative diseases is considered to be an integral part
of the diagnostic process pointing to the correct classification of the individual diseases and to
the choice of the most suitable type of therapy. This article describes the immunophenotype of
particular types of B-lymphoproliferative disorders included in the World Health Organization
classification (WHO) and the prognostic importance of some markers. The panel of specific monoclonal
antibodies directed to B-cell lineage used in our department is displayed.
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