This review summarizes of present views on therapeutic indications of human albumin solutions therapeutic indications.Human albumin solutions have been used for treatment for several decades, nevertheless,opinions on their use are very different.Acceptable indications are:hypovolaemia therapy in patients with acute nephrosis,in pregnancy,in septic shock in children,in patients at risk for coagulation disorders;extensive burns;cardiac and paediatric surgery,liver transplantation; prevention and treatment of ovarian hyperstimulation syndrome;exchange transfusion for treatment of hyperbilirubinaemia in neonates;decompensated hepatic cirrhosis with ascites;in patients with cirrhosis and spontaneous bacterial peritonitis;Adult Respiratory Distress Syndrome;therapeutic plasmapheresis and especially when other colloid solutions are contraindicated or dose limited.

        Key words: albumin,indications,side effects,contraindication