Analysis of Accidental Drug Intoxications in Children Hospitalized at the Children's Faculty
Hospital in Bratislava in the Years 1996 - 2000
Kuželová M.1, Plačková S.2, Kovács L.3, Benedeková M.4, Riedel R.5, Cagáňová B.2, Seginko J.1, Švec P.1
Katedra farmakológie a toxikológie FaF UK, Bratislava1 vedúci prof. MUDr. P. Švec, DrSc. Toxikologické informačné centrum, Klinika pracovného lekárstva a toxikológie LF UK, FNsP akad. L. Dérera, Bratislava2 vedúca PharmDr. S. Plačková, MPH. II. detská klinika LF UK, DFNsP, Bratislava3 prednosta prof. MUDr. L. Kovács, DrSc., MPH. I. detská klinika LF UK, DFNsP, Bratislava4 prednostka doc. MUDr. M. Benedeková, CSc. Detská klinika anesteziológie a intenzívnej medicíny SZU, DFNsP, Bratislava5 prednosta prof. MUDr. T. Šagát, CSc. |
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Summary:
The authors analyze accidental drug intoxications in children, who were hospitalized for this diagnosis at the
1st and 2nd Children's Clinics ofLF UKand Children's Clinic of Anesthesiology and Intensive Medicine (DKAIM)
of Children's Faculty Hospital with Policlinic in Bratislava in the period of 1996 - 2000. The analyzed cohort (43.7%
of all drug intoxications) included 129 child patients up to 6 years of age. Two-year children constituted the most
frequent group. Flunitrazepam was the most frequent drug in accidental intoxications and the most frequent
pharmacological group was that of analgesic drugs - antipyretic and antirheumatic ones. Accidental intoxication
with paracetamol and ibuprofen formed a large group of intoxications. Children from the observed group
consumed the preparations most frequently in a solid drug form (87.1%), color drug forms (56.1%) and preparations
wrapped in blister packs (66.4%) prevailed. In the analyzed cohort there were 13 cases of serious intoxications
and one case of heavy intoxication. Serious and heavy intoxications were most frequently encountered after
flunitrazepam.
Key words:
accidental intoxication, children, drugs, degree of intoxication
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