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CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ |
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Česky / Czech version | Vnitř. Lék., 48, 2002, No. 10, p. 959 - 961 |
Acid-base Balance in Haemodialyzed Patients Vnitřní lékařství, 48, 2002, č. 10, s. 959 - 961 1Nefrologická klinika Lekárskej fakulty UPJŠ a FN L. Pasteura, Košice, Slovenská republika, prednosta prof. MUDr. M. Mydlík, DrSc. 2Oddelenie klinickej biochémie FN L. Pasteura, Košice, Slovenská republika, primár MUDr. A.Molčányiová |
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Summary: Metabolic acidosis is a known complication of chronic renal failure. Maintenance of the pH within
the reference range is important for influencing manifestations of the uraemic syndrome and the
mortality of haemodialyzed patients. Intermittent bicarbonate haemodialysis should ensure the
acid-base balance within the reference range also during the interval between haemodialyzations.
In a short-term prospective study 20 haemodialyzed patients with chronic glomerulonephritis and
pyelonephritis were examined. The authors assessed indicators of the acid-base balance (pH,
HCO3
-, pCO2) at the time of two haemodialyses and during the interval between haemodialyses.
The blood flow in the dialyzation monitor was 300 ml/min. and the flow of the dialyzation solution
500 ml/min. The bicarbonate concentration in the dialyzation solution was 34 mmol/l. The duration
of haemodialysis was 4 hours three times per week. Bicarbonate haemodialysis with a bicarbonate
concentration of 34 mmol/l in the dialyzation solution ensured also during the interval
between dialyzations a pH in the reference range in patients with chronic renal failure.
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