We report anaesthesia management for liver resection in a patient with supposedlarge blood loss,because of close relations of the hepatic metastasis of colorectal carcinoma to the portal and inferior caval vein. To minimize blood loss we used combination of an acute normovolemic haemodilution (ANH) and a low central venous pressure (CVP) anaesthesia. The 2000 g of whole blood was withdrawnafter induction of general anaesthesia.TheCVPwas maintained below5mmHg during resection of hepatic parenchyma. The right hepatectomy with subsegmentomy IV A was performed using of total vascular exclusion.The estimated blood loss was 2000 ml.The patient was extubated withoutcomplications the first day after surgery with haematocrit value 0.35 and haemoglobin level 113 g/dl. Except application of antithrombin III (1000 units) there was no necessity to administrate another allogenic blood products.

        Key words: hepatic resection – low CVP anaesthesia – acute normovolemic haemodilution