Premature Separation of the Placenta – Etiology and Risk Factors
Procházka M., Kudela M., Lubušký M., Větr M., Hrachovec P., Zielina P.
Porodnicko-gynekologická klinika LF UP, Olomouc, přednosta prof. MUDr. M. Kudela, CSc. |
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Summary:
Objective: Placental abruption complicates approximately 1% of all pregnancies and remains a significant
cause of both maternal and fetal morbidity and mortality. Several risk factors are associated with
this complications, but a clear causal relation is diffucult to establish.
The aim of the study: The aim of the study was to determine and identify risk factors for placental
abruption.
Design: Retrospective cohort study.
Setting: Dept. of Obstetrics and Gynaecology, Medical Faculty of Palacký University, Olomouc.
Subject and Method: Retrospectively gathered cohort of 180 women was compared to 198 healthy
women. We have focused on anthropometric, sociodemographic, behavioral, obstetric and fetal parameters.
Statistical evaluation was done by Statsoft, Inc. (2001) Statistika CZ (Software system data analysis),
version 6.
Results: The incidence of the placental abruption was 0.89%. We have confirmed the following risk factors
as statistically significant (p values are given): Low-degree education (0.00002), prepregnancy
weight of the mother (0.00), weight gain in pregnancy (0.00), higher parity (0.0272), smoking (0.03847),
preeclampsia (0.00889), chorioamnionitis (0.00), premature rupture of membranes (0.00), recurrent
spontaneous abortions (0.00), positive family history of deep venous thrombosis (0.0007) and intrauterine
growth retardation (0.0386).
Conclusion: Placental abruption has a large number of potential risk factors. The true biological cause
and its etiopathogenic role is still to be elucidated.
Key words:
placental abruption, risk factors, etiology
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