Two pilot studies were performed in 6 180 women during 1. 11. 2001 – 1. 2. 2002 and 1. 3. 2002 – 1. 6. 2002. Their aims were to answer several questions discussed in the context of a recently planned screening programme in the Czech Republic. How many asymptomatic women would take advantage of the preventive breast examination? Is it possible to introduce the system of one-day-negative diagnostics? Can the concept of the screening program be based on the newly introduced units of integrated breast diagnostics? How many women with malignant tumor or with benign breast disease may be hidden in the so-called asymptomatic group? The results of the pilot screening project are in full accordance with the studies carried out in other countries. One-day diagnosis of the negative cases is feasible in specialized units and the complete diagnostics including preoperative biopsy in one site can become the standard which fulfills the EUSOMA criteria as well.

        Key words: unit of integrated mammary diagnostics – breast cancer screening – one-day negative diagnostics