Summary:
The term „Hibernating myocardium“ refers to the presence of a chronic left ventricular dysfunction that could
be partially or completely improved after revascularization. Formerly, the myocardial hibernation was conside-
red to be an adaptive response to a sustained reduction of the resting myocardial blood flow. Recently, several
studies with positron emission tomography have revealed a normal or almost normal resting myocardial blood
flow. The reduced coronary flow reserve of the hibernating myocardium brings about multiple episodes of
demand-induced ischemia and may evoce recurrent stunning of the myocardium. It is the basis of structural
changes in the myocardium and the contractile dysfunction. Cellular degeneration rather than adaptation
prevails in the hibernating myocardium. The longer the process continues, the smaller is the chance for
a complete structural and functional recovery after the reperfusion. Thus the early revascularization becomes
important for the patients with hibernating myocardium.
Key words:
coronary artery disease, left ventricular function, hibernating myocardium
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