Basal Concentrations of FSH (Follicle Stimulating Hormone) as a Predictor
of Succes of IVF-OCSI Cycle
Toporcerová S., Adam J., Toporcer T., Hredzák R., Ostró A.
II. gynekologicko-pôrodnícka klinika LF UPJŠ a FN, Košice, prednosta prof. MUDr. A. Ostró, CSc. |
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Summary:
Objective: To evaluate the predictive value of basal follicle-stimulating hormone (FSH) levels in relation
to the ovarian reserve and to establish their effect on IVF success.
Design: Retrospective clinical study.
Setting: 2nd Department of Gynaecology and Obstetrics, Medical Faculty and L. Pasteur University Hospital
Košice.
Methods: 155 IVF cycles were evaluated in relation to the basal FSH levels. Several parameters were
regarded – duration of stimulation, gonadotrophins dosage, number of oocytes, oocyte quality, fertilization
ratio, number of embryos, pregnancy rate and miscarriage rate.
Results: Statistically significant correlation in relation to basal FSH levels was established in case of number
of oocytes and number of embryos (p<0,05). Other parameters were not correlated to basal FSH
levels. There was not established lowerpregnancy rate in patients with elevated basal FSH levels.
Conclusions: On basis of this study results we can observe that basal FSH concentrations give us some
information about ovarian reserve, but they neither inform about oocyte quality nor predict IVF success.
Key words:
IVF, basal FSH, ovarian reserve, poor responders, prognosis
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