Analysing retrospectively records of patients hospitalised in an inpatient unit at the University Psychiatric Department, Brno with schizophrenia and related disorders in 2000, we found that 95/133 (71%) of all patients took atypical antipsychotics and 36/133 (27%) took a combination of antipsychotics before admission. Almost all of them left the unit with antipsychotics treatment, the percentage of atypical antipsychotics did not change much (68%) nor the percentage of combinations (28%). The percentage agrees with published European studies. Risperidone was used most frequently before hospitalisation (55/95, i.e. 57%), on discharge the most frequent was olanzapine (56/125, i.e. 45%). Most frequent was on admission and discharge a combination of a typical and an atypical antipsychotic (45%, 44% of the combinations). Combinations were prescribed most frequently (39% of the patients with this diagnosis) to patients with schizoaffective disorder. On admission we did not find that any of the possible combinations was preferred, on discharge the most frequent combination was olanzapine or clozapine and sulpiride (29% of all combinations).

        Key words: antipsychotics, schizoaffective disorder, clozapine, olanzapine, risperidone.