The authors present results of research in the experiences of Czech patients who had undergone bone marrow transplantation. Qualitativemethodology based on non-structured interviewswas used in the research. Bone marrow transplantation is a serious event in the life of the patient. The method sets high demands on adaptability of the patient; health care providers and family have also an important role. In interviews several topics appeared: uncertainty, anxiety and fears, important role of information, ways of coping with uncertainty and fears, ways of coping with demands of therapy, role of physicians and role of the family.

        Key words: qualitative research - bone marrow transplantation - adaptation to serious illness.