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CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ |
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Česky / Czech version | Čes. a slov. Neurol. Neurochir., 65/98, 2002, No. 6, p. 410–420. |
Experience with Radiosurgery
in Mesiotemporal Epilepsy Vojtěch Z., Vladyka V1., Liščák R., Kalina M., Novotný J. Jr.1 Neurologické oddělení Nemocnice Na Homolce, Praha 1Oddělení stereotaktické a radiační neurochirurgie Nemocnice Na Homolce, Praha |
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Summary: An outline of experimental and clinical data concerning the radiosurgical treatment of epilepsies is
given. The article deals with 13 patients who were treated at our institution for intractable mesial
temporal lobe epilepsy with mesial temporal sclerosis between November 1995 and May 1999. In these
patients the duration of epilepsy was long and encephalopathic neurological and neuropsychological
signs were present in virtually all. Epileptological results which are worse than those in the only one
comparable published study are discussed. Complex partial seizures frequency tended to rise between
4th and –10thmonths after irradiation and then fell to approximately one fourth of the original frequency
two years after irradiation. We found partial upper lateral quadrant anopia as a permanent side effect
in 2 patients. The poor effect of irradiation led us to epilepsy surgery in 2 patients. MRI changes after
radiosurgery and choice of optimal radiosurgical plans are given. Collateral oedema was seen in 8
patients, started earlier and was found more often in those irradiated with higher doses. In 3 of them
it had an expansive character and in 2 clinical signs of intracranial hypertension were present.
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