The authors describe available knowledge reported in the literature on the treatment of leukoplakia oris. Conservative methods are used. They discuss the effect of beta-carotene, retinol and retinoids. As to vitamins, they mention experience assembled with vitamin C, alpha-tocopherol and with a combination of antioxidants.

        Key words: leukoplakia oris – beta-carotene – retinoids – alpha-tocopherol