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  Česky / Czech version Čes. a slov. Neurol. Neurochir., 67/100, 2004, No. 3, p. 204–207.
 
Primary malignant lymphoma of the brain – ten-year survival 
Vaverka M., Kala M. 

Neurochirurgická klinika FN a LF, Olomouc
 


Summary:

       Primary non-Hodgkin lymphoma of the CNS in an immunocompetent individual is considered a tumor with low frequency of occurrence and solitary cerebellar localization is rare. After verification of the diagnosis with biopsy, radiotherapy with chemotherapy is considered the gold standard of therapy of these tumors. Prognosis is generally unfavorable; survival time rarely reaches three years, most of the time it is only months. In the presented case, conventional radiotherapy and chemotherapy followed a radical microsurgical operation, as the CT picture of the structure was considered a meningioma of the tentorium. Histological examination showed a lymphoma with insignificant expression in B-markers and a prominent portion of epitheloid-histiocytary elements and T-lymphocytes. The patient has survived with a high quality of life without signs of the disease for more than ten years. Review of available literature provided a few cases where a radical surgery also positively influenced the survival time. Communication presents a review of current treatment options.

        Key words: lymphoma, brain, neurosurgery
       

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