Issues in early diagnostics of operated spinal metastases
Řehák S.,1 Málek V.,1 Náhlovský J.,1 Odrážka K.,2 Ryška P.,3 Kaltofen K.,1 Česák T.,1 Melichar B.,2 Kanta M.1
1Neurochirurgická klinika, FN, Hradec Králové, 2Klinika onkologie a radioterapie, FN, Hradec Králové, 3Radiologická klinika FN, Hradec Králové |
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Summary:
Development of surgical methods and elaboration of approaches to the spine have made surgery feasible
for most metastatic processes in the spine. However, delayed determination of the correct diagnosis
and thus late initiation of adequate treatment remain the limiting factors for successful treatment.
In our group of 69 patients, local back pain was the initial symptom in 81 % of patients and
preceded the determination of diagnosis of metastatic spine disease on average by 11 weeks. The
development of neurological deficit directly depends on the degree of spinal compression. At the time
of diagnosis of metastatic spine disease, 70 % of patients had manifest neurological symptoms that
had developed for an average of 15 days. The ability to walk at treatment onset is the most important
prognostic factor in metastatic involvement of the spine. In the studied group at the time of diagnosis,
55 % of patients were confined to bed for a neurological deficit and had been unable to walk
for an average of 5 days. Analysis of our group indicates that graphical determination of diagnosis
of metastatic spine disease was often made late, even when symptoms of spinal compression had been
clearly expressed for several days. The diagnosis must be based both on patient history of malignant
neoplasm and on detailed clinical examination. Radiological imaging methods facilitate exact determination
of the location and extent of metastatic disease in the spine. MRI is today considered the examination
of choice when spinal metastasis is suspected. It is necessary to increase the awareness of physicians
and right at suspicion of metastatic spine disease, expedite the use of diagnostic methods to
determine the diagnosis. This represents the only way to satisfactory results and prevention of the devemetastaticlopment
of irreversible neurological changes. In the presence of a severe preoperative neurological deficit,
even surgical decompression of the spine often does not succeed in substantial improvement of motor
deficit in the limbs.
Key words:
spinal metastases, spinal compression, late diagnosis
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