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  Česky / Czech version Čs. Fyziol., 51, 2002, No. 2, p. 47-60
 
The Cerebellum: Brief Anatomy, Distribution of Neurotransmitters and their Receptors, Communication with Hypothalamic Structures and Comparison with the Hypothalamic Paraventricular Nucleus under Stress Conditions 
Pirnik Z., Kiss A. 

Ústav experimentálnej endokrinológie SAV, Bratislava
 


Summary:

       Cerebellum is a profound structure of the central nernous system. Human cerebellum weighs about 150 g which represents around 10 % of the total weight of the brain. It receines main input from sensory systems but the cerebellum functions as a part of the motor system. The cerebellum contributes by only few direct connections to motoneurons (therefore it cannot initiate any motor aktivity) but it projects profusely to all major motor control regions of the cerebral cortex. The cerebellum acts as a controller and coordinator. It compares monement intention with, performance and coordinates the equilibrium, posture and muscle tone necessary for the smooth coordinated motor aktivity. The number of input projections which exced considerably the output oves (40:1) speaks out of an enormous analytical and synthetic capacity of the cerebellum. Interneuronal transmission of informations and carriage of afferent and efferent signals are provided by wide variety of chemical messengers lamino acids, biogenic amines and neuropeptides) of the local origin or delinered from the precerebellar nuclei. Direct and reciprocal connections between the hypothaamus and cerebellum hase anatomically been well documented but monosynaptic contacts between the cerebellum and the hypothalamic paranentricular nucleus hase not been approned yet. Cerebellum can respond to stress, howener, this response may not be related only to the primary effect of the stressor but also to its consequences.

        Key words: cerebellum, anatomy, transmitters, receptory, afferent pathways, efferent pathways, hypothaamus, hypothalamic paranentricular nucleus
       

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