Abstract Acute Myocardial
Infarction as a Result of External Compression by the Spreading Bronchogenic Adenocarcinoma
Bulava A., Škvařilová M., Marek D., Kociánová E., Lukl J.
I. interní klinika Lékařské fakulty UP a FN, Olomouc, přednosta prof. MUDr. Jan Lukl, CSc. |
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Summary:
The case report describes a rare cause of acute myocardial infarction. 68-years old man with the
cancer triplicity (follicular and papilar carcinoma of the thyroid gland, Grawitz tumor, bronchogenic
carcinoma with generalization) was admitted to the intensive care unit for the sudden onset
of chest pain, positivity of cardioselective enzymes and signs of cardiogenic shock. Echocardiographic
examination proved diaphragmatic akinesis with low left ventricular ejection fraction
about 30 %. The acute coronary angiogram revealed unimportant atherosclerotic narrowing of
the left coronary artery and a long significant stenosis in the proximal portion of the right coronary
artery untypical for atherosclerotic lesion suspicious of extramural compression. A pathological
vascularization to the extramyocardial region was documented during right coronary
angiogram. The patient was treated conservatively and finally transferred to the pulmonary
disease department, where he died of progression of the cancer disease two months later. Postmortem
examination found spreading of the bronchogenic adenocarcinoma to the pericardium
along the course of the right coronary artery, but neither direct infiltration of the vessel wall by
the tumor nor atherosclerotic disease of the proximal portion of the right coronary artery were
proved. These findings together with the coronary angiogram demonstrate a rare cause of the
myocardial infarction due to the extramural compression by the malignant tumor.
Key words:
Acute myocardial infarction - Right coronary artery - Coronary angiogram - Tumor -
Compression
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