The authors present the čase of a 60year old female with a short history of dyspnoea, hospitalised for predominant right heart failure. Based on echocardiographic pattern of restrictive cardiomyopaťhy and the clinical picture, cardiac amyloidosis was suspected. However, no laboratory tests or other supporting examinations, including liver and greater omentum biopsy, led to the correct diagnosis. The unanimous diagnosis of primary amyloidosis was established by means of endomyocardial biopsy. Due to the fast progression of heart failure any further therapeutic possibilities were limited. In order to consider causal treatment of this disease, endomyocardial biopsy should be performed early, once cardiac amyloidosis is suspected.

        Key words: heart failure, cardiac amyloidosis, echocardiography, endomyocardial biopsy.